• br Disclosures br Acknowledgements This work

  2019-11-02

  

  Disclosures Acknowledgements This work was supported in part by grants from the Ministerio de Ciencia e Innovación, Spain (SAF2010-22051) and Xunta de Galicia, Spain (INCITE08PXIB203092PR). Introduction Ca is a key element in cardiac excitation–contraction (EC) coupling. In each heartbeat,

• br Results br Discussion br Materials and Methods

  2019-11-02

  

  Results Discussion Materials and Methods Acknowledgment This work was funded by the Collaborative Research Centre (SFB) 807 of the German Research Foundation (DFG) and supported by the state of Hessen (Center for Biomolecular Magnetic Resonance) and the German Research Foundation (DO545/

• In conclusion we developed a new CysLT and

  2019-11-01

  

  In conclusion, we developed a new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model that can be useful for screening both CysLT2 receptor and CysLT1/2 receptor antagonists. In addition, we have shown that the dual CysLT1/2 receptor antagonist ONO-6950 can exert protective effect agai

• br Prostaglandin D PGD is

  2019-11-01

  

  Prostaglandin D (PGD) is derived from the metabolism of arachidonic a83 synthesis by cyclooxygenases and downstream PGD synthases. In the immune system, PGD is mainly produced by mast cells but also although at lower levels, by macrophages and Th2 lymphocytes. PGD binds to three different recepto

• Compound was prepared from chloroindole

  2019-11-01

  

  Compound was prepared from 6-chloroindole () () by acylation, to give , and subsequent reduction to give . The thiazole was then installed using conditions developed by Buchwald and co-workers to give . Hydrolysis of the ester yielded the thiazole W146 derivative (). Derivatives and were prepar

• br Materials and methods br Results br Discussion

  2019-11-01

  

  Materials and methods Results Discussion In this work, we have studied the contribution of different pathways to the slow but stable progression of replication forks through DNA damaged by MMS [15]. The in vivo analysis of DNA replication forks along a specific chromosome of S. cerevisiae h

• bethanechol chloride Dgat mice however had less adipose

  2019-11-01

  

  Dgat−/− mice, however, had less adipose tissue, as reflected by lower total fat pad weights and body triglyceride content. Because of these findings, we hypothesized that, although Dgat−/− mice could make triglycerides through non-DGAT pathway(s), their triglyceride synthesis capacity might not be e

• While several C terminal peptides have been reported

  2019-11-01

  

  While several C-terminal peptides have been reported to have modest (astressin) or substantial (astressin2-B, antisauvagine-30) subtype selectivity for the CRF2 receptor (), [125I]YP20 is the first reported small analog of the C-terminus of CRF exhibiting subtype selectivity for the CRF1 receptor vs

• Lipolysis and fatty acid oxidation are two

  2019-11-01

  

  Lipolysis and fatty pgp inhibitors oxidation are two important mechanisms involved in fat reduction. Over stimulation of lipolysis increases the level of FFAs in the serum and causes metabolic perturbation (Koutsari and Jensen, 2006). A large inflow of FFAs to the mitochondria may lead to mitochond

• PF-06447475 Accurate equilibrium predictions of CO containin

  2019-11-01

  

  Accurate equilibrium predictions of CO2 containing mixtures, however, are challenging with traditional equations of state. The reason for this may be that CO2 has a large quadrupole moment. The large quadrupole moment of CO2, as well as size asymmetry, are for instance believed to be the reasons for

• Sensory gating describes a filter mechanism

  2019-11-01

  

  ‘Sensory gating’ describes a filter mechanism protecting the central nervous system from sensory overload by inhibiting behaviorally irrelevant input (Boutros et al., 2004, 2008). This permits KN-93 Phosphate australia to a changing contextual environment (Fruhstorfer et al., 1970; Grunwald et al.,

• br Discussion The present study found cholinesterase activit

  2019-11-01

  

  Discussion The present study found cholinesterase activity in Saccostrea sp. to vary significantly among three tissue types (digestive gland, gills, adductor muscle) and to respond differentially to four toxicants, three of which were non-organophosphates. Furthermore, a comparison of enzyme acti

• The Fontan circulation When first described in

  2019-11-01

  

  The Fontan circulation When first described in 1971, the Fontan operation ushered in a new paradigm in the care of children born with the varied forms of complex congenital ro bio 2 disease (CHD) characterized by a single effective pumping chamber.1., 2. This procedure, which creates a total cavop

• br Materials and methods br Results br Discussion In

  2019-11-01

  

  Materials and methods Results Discussion In particular, we showed that pancreatic neuroendocrine tumor fty recognize cAMP as a stimulatory signal for cell proliferation. Conversely, cAMP was found to have an inhibitory effect on cell proliferation in bronchial carcinoids cells. The diverge

• The genes corresponding to TVAG

  2019-11-01

  

  The genes corresponding to TVAG_263740, TVAG_487600, TVAG_282090, TVAG_170370, and TVAG_148010 seem to be the less expressed, and undetectable by proteomics approach. In comparison, in other T. vaginalis strains, and experimental conditions, they show very few or null EST\'s reports [4]. Concludi

14956 records 934/998 page Previous Next First page 上5页 931932933934935 下5页 Last page