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Although the activities interactions and
2020-07-27
Although the activities, interactions and nucleocytoplasmic traffic of mucosal alpha genus HPV E7 oncoproteins have been well documented (McLaughlin-Drubin and Munger, 2009), much less is known about the cutaneous beta genus HPV E7 proteins. The cutaneous HPV8 E7 oncoprotein has a weaker interaction
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Thus in the present study CRF and CRF receptor
2020-07-27
Thus, in the present study CRF1 and CRF2 receptor-deficient mice are used to assess the specific role for each of the two known CRF ati stock quote subtypes in opiate withdrawal-induced cognitive dysfunction. For this purpose, the NOR task, a paradigm commonly employed to examine recognition memory
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In this study a GMI of was associated with high
2020-07-27
In this study, a GMI of 1.0 was associated with high sensitivity above 90%, specificity below 30% and higher negative predictive value. However, this cut-off couldn\'t have been optimal because of the lower level of Youden J Index which was S63845 is suggested that long term prospective studies invo
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In this study we examined the role of a well
2020-07-27
In this study we examined the role of a well characterized genetic polymorphism in the COMT gene in mediating cognitive antipsychotic treatment effects in first episode psychosis (FEP). We considered catechol-O-methyltransferase (COMT) to be a potentially important baseline consideration in a pharma
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br Acknowledgements br This work was
2020-07-25
Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (Grant No.: 30260088) and the prophase research for National “973” Project of China (Grant No.: 2007CB116203). The DNA sequences of Hbvp1 and the Hbvp1 promoter were deposited in GenBank, an
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Many studies have used paradigms based on
2020-07-25
Many studies have used paradigms based on animal models to understand human emotional behavior because it appears to be correlated with fear- and anxiety-related defensive patterns in non-human mammals (Blanchard et al., 2001). In this case, defensive reactions are used to study the neural substrate
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In contrast to PEGylated proteins which tend to have reduced
2020-07-25
In contrast to PEGylated proteins which tend to have reduced sb chemical in the body relative to their native counterparts, proteins conjugated to albumin tend to accumulate in certain locales in vivo. This means that albumin-based drug carrier systems have particular applications in the field of c
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In the current study although EP agonist
2020-07-25
In the current study, although EP4 agonist was the most effective in relaxing corpus cavernosum, it did not affect the neuronally-mediated relaxation. On the other hand, both alprostadil and iloprost, which were less effective as direct relaxants, potentiated EFS-induced relaxation of rat corpus cav
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CD is a key co stimulation surface marker that can
2020-07-25
CD28 is a key co-stimulation surface marker that can be detected in all peripheral T Zafirlukast in newborns, and the proportion of CD28bearing T cells reduces progressively with age [reviewed by (Fagnoni et al., 1996; Weng et al., 2009)]. Therefore, CD28nullCD8+ T cells are one of the most acknowle
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Besides having a remarkable progestogenic effect an addition
2020-07-25
Besides having a remarkable progestogenic effect, an additional characteristic of DRSP is its strong antimineralocorticoid effect and antiandrogenic action [11]. DRSP is characterized by an antimineralocorticoid effect that is stronger when compared to progesterone. The decreasing synthesis of proge
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Recently cross talk between DDR and the insulin
2020-07-25
Recently, cross-talk between DDR2 and the insulin receptor and between Notch1 and DDR1 was proposed. Stimulation of cells with collagen I and insulin promotes Tyr740 as well as total tyrosine phosphorylation of DDR2 receptor to a greater extent than the phosphorylation stimulated by collagen I alone
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The TELI results of DNA damage responses to CAA
2020-07-25
The TELI results of DNA damage responses to CAA and SO then informed our choice of bacterial strains in subsequent experiments. We investigated E. coli cellular survival in response to CAA and SO exposure by determining the sensitivity of a number of E. coli strains, each possessing single or multip
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br Introduction Malaria remains a serious
2020-07-25
Introduction Malaria remains a serious parasitic disease in tropical areas due to its high morbidity and mortality rates. It is estimated that 212 million cases occurred globally in 2015, leading to 429, 000 deaths, most of which were in children aged under 5 years in Africa [1,2]. The protozoans
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LTD and LTC cause contraction in the rat
2020-07-25
LTD4 and LTC4 cause contraction in the rat stomach and these contractions are sensitive to CysLT1 receptor antagonists (Goldenberg and Subers, 1983, Miura et al., 1992, Miyata et al., 1995). However, effects of other leukotrienes in the gastric contraction and inhibitory effects of potent, selective
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br Acknowledgement This research was supported by a grant
2020-07-25
Acknowledgement This research was supported by a grant from the National Research Foundation of Korea (NRF-2013R1A1A2011238) funded to Young-Mi Lee. Introduction Stroke is considered a serious disease with high morbidity and high mortality. More than 6 million deaths are reported each year wo
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