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In our studies of leucine and BCH in pancreatic
2023-05-30

In our studies of leucine and BCH in pancreatic islets and clonal insulin cell lines, we noticed that leucine was a slightly stronger stimulant of insulin release. Previous studies showed that leucine can be metabolized to CO2[11], [12], [13], [14] and can increase acetoacetate in pancreatic islets
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Hypoxia induced replication arrest has been demonstrated
2023-05-30

Hypoxia-induced replication arrest has been demonstrated in a variety of organisms in addition to mammals; including Zebrafish , , and (brine shrimp) which have been shown to survive for 4 years and longer in anoxic conditions . Despite this breadth of study, little is known about the mechanism of h
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The use of FTAI can overcome
2023-05-30

The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable vx 765 follicle. Pregnancy rates obtained with FTAI may be comparable or better than those obtained after AI
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The use of FTAI can overcome
2023-05-30

The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable PRX-08066 follicle. Pregnancy rates obtained with FTAI may be comparable or better than those obtained afte
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The reasons why antibiotic treatment
2023-05-29

The reasons why antibiotic treatment may be detrimental are diverse. First, it may result in disruption of multifaceted microbe–microbe, as well as microbe–host, interactions that are key for the maintenance of homeostasis within this ecosystem. This can lead to the expansion of pathogenic microorga
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Introduction Antimicrobial resistance is a growing health
2023-05-29

Introduction Antimicrobial resistance is a growing health threat worldwide that has been associated with incorrect prescription and overuse of Agar synthesis [1]. Considering that physicians play a central role in antibiotic usage, a better understanding of their prescribing behaviours and their k
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Natural compounds present in medicinal and or nutritional pl
2023-05-29

Natural compounds, present in medicinal and/or nutritional plants as well as in macrofungi sources, have stimulated a great interest from the pharmaceutical industry. Different natural compounds such as phenolic compounds, alkaloids, terpenoids among others, have shown strong antiangiogenic effects
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Various antiangiogenic drugs have been analyzed
2023-05-29

Various antiangiogenic drugs have been analyzed over the last few years; noteworthy, bevacizumab, a monoclonal antibody against VEGF-A, alone or in combination with cytotoxic agents showed interesting results in terms of radiographic response rates and progression-free survival in initial phase 2 st
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Immunohistochemistry in tissue samples showed the expression
2023-05-29

Immunohistochemistry in tissue samples showed the expression of several nuclear receptor co-activators, including NCOA1, NCOA2, NCOA3, CREBBP, and EP300, in 85–100% of Melatonin tumors even some of which lacked AR expression (Boorjian et al., 2009). Knockdown of each co-activator also resulted in s
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br Obstructing SNARE zippering Sharma et al
2023-05-29

Obstructing SNARE “zippering” Sharma et al. demonstrated for the first time that in the postmortem AD brains, the level of SNARE complex formation, which is necessary for driving synaptic vesicle fusion at the presynaptic active zone, is significantly reduced [123]. In the absence of changes in e
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On the other hand it
2023-05-29

On the other hand, it is important to note that FR is different from the regulation of daily/circadian rhythms [44]. Based on models of physical systems [45], [46], it has been hypothesized that fractal physiological fluctuations reflect a network of elaborate regulatory processes interacting across
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br Downstream signalling of AKT A consensus phosphorylation
2023-05-29

Downstream signalling of AKT A consensus phosphorylation motif has been described for AKT substrates: R-X-R-X-X-S/T-B where X represents any amino metabolic enzymes and B represents bulky hydrophobic residues (Alessi, Caudwell, Andjelkovic, Hemmings, & Cohen, 1996). Numerous AKT substrates have b
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The functional observations from the present study
2023-05-29

The functional observations from the present study are based on neoplastic ikk pathway (HSY), and comparative expressions between normal salivary and pleomorphic adenoma tissues. However, there is a paucity of information on AhR expression and function in normal salivary gland, not neoplastic, cells
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CGRP 8-37 (rat) br Co http www apexbt
2023-05-29

Conclusions This paper is the first meta-analysis about the association between SRD5A2 V89L polymorphism and hypospadias risk. The results of this meta-analysis have revealed that V89L polymorphism definitely increases the risk of hypospadias, and the C allele is a genetic risk factor for hypospa
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The obtained results indicate that even
2023-05-29

The obtained results indicate that even when the impairment of the same forms of memory are present, amnesia can develop in different ways. Impairment of memory reconsolidation in the conditioned food aversion model through both the serotonin receptor antagonist and the antagonist of NMDA glutamate
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